View Full Version : St John's Wort and SAM-E

07-26-2011, 10:57 PM
Has anyone tried either of these? What do you think?

11-29-2011, 11:15 PM
Hello sweetlee123,

I have tried both and have found SAM-E to be amazing, with only a so-so effect from St. John's wort. I must say though, that I haven't tried St. John's wort long enough to give it a good go, as much as I have with SAM-E. I also suffer from extreme moodiness and depression when I have my periods, and this seems to be entirely mitigated by SAM-E. SAM-E is a naturally occurring amino acid in our bodies, that helps with joint health and mood elevation because it can pass the blood-brain barrier.

Interestingly enough, I have had my husband take it, and he finds that the results are minimal to nominal at best. I definitely would recommend trying it if it doesn't harm your medical regimen at all. :)